MR CLEAN NOIV

The MR CLEAN-NO IV trial is a Multicenter Randomized CLinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands investigating the added benefit of intravenous alteplase prior to intra-arterial thrombectomy in stroke patients with an intracranial occlusion of the anterior circulation.

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Final patient included in the MR CLEAN NOIV

On the 28th of Oktober 2020, the final patient (with registered consent) was included in the MR CLEAN NO IV trial.

Results of the MR CLEAN-NO IV trial have been published in the New England Journal of Medicine on November 11, 2021: https://www.nejm.org/doi/full/10.1056/NEJMoa2107727.


Kind regards,

MR CLEAN-NO IV executive committee on behalf of the CONTRAST consortium:
Yvo Roos,
Charles Majoie,
MR CLEAN-NO IV principal investigators