Rationale and aim
Because of recent developments, findings in earlier observational studies like the MR CLEAN Registry may not be broadly applicable to current clinical practice anymore. Moreover, the MR CLEAN Registry and other registries lacked a level of detail to address clinically relevant questions, such as the outcomes of EVT in patients with a demarcated infarct or with specific thrombus or vessel characteristics on imaging, or with the use of newer devices. And notably, regulatory and re-imbursement bodies are increasingly seeking for real-world data on implementation and follow-up of new devices and techniques. The DIVINE registry will gather highly detailed data on EVT in patients with acute ischaemic stroke in current clinical practise in the Netherlands and use this data to answer key clinical questions.